Reishi mushrooms, often referred to as the “Mushroom of Immortality,” have been used for centuries in traditional Chinese medicine to promote longevity, enhance immunity, and reduce stress. With modern scientific research backing many of their benefits, reishi mushroom supplements have become a popular choice for those seeking to boost overall health.
In this guide, we’ll explore the key benefits of reishi mushrooms, what to look for in a high-quality supplement, and provide our top recommendations for the best reishi mushroom supplements available today.
Our Top Picks for Reishi Mushroom Supplements
1. Best Overall: Fresh Nutrition Organic Reishi Mushroom Capsules
2. Best High-Potency Formula: Double Wood Reishi Mushroom Capsules
3. Best for Energy & Cognitive Function: Wellnest.Store Organic Reishi Mushroom Supplement
4. Best for Relaxation & Sleep: Troop Reishi Mushroom Gummies
5. Best for Immune Support & Strength: Nutricost Reishi Mushroom Capsules
6. Best Budget Option: Horbäach Reishi Mushroom Capsules
1. Best Overall: Fresh Nutrition Organic Reishi Mushroom Capsules
4.4 out of 5(1313+) from Amazon

Price: $19.97
Fresh Nutrition Organic Reishi Mushroom Capsules provide a potent 1500mg per serving, making it one of the strongest reishi supplements available. Sourced from organic red reishi (Ganoderma lucidum & Ganoderma applanatum), this supplement is third-party tested, vegan, and non-GMO, ensuring high purity and quality. With a dual extraction method (hot water & alcohol), it maximizes the bioavailability of beneficial compounds like alpha-glucan (40%+ content) for superior immune support.
Key Benefits
- High Potency Formula – 1500mg per serving for maximum effectiveness.
- Rich in Alpha-Glucan – Contains more than 40% alpha-glucan, supporting immune function.
- Dual Extraction Method – Ensures better absorption and higher bioavailability of active compounds.
- Pure and Clean Ingredients – Free from pesticides, herbicides, fillers, and additives.
- Made in the USA – GMP-certified and FDA-registered facility for safety and quality assurance.
Main Ingredients
Each serving (3 capsules) contains:
- Organic Reishi Mushroom Extract (Ganoderma lucidum & Ganoderma applanatum) – 1500mg
- Vegetarian Capsules (No artificial additives or fillers)
Notable Advantages
✔ Certified Organic & Third-Party Tested – Ensures purity, potency, and safety.
✔ Vegan, Non-GMO, Gluten-Free, and Soy-Free – Suitable for various dietary needs.
✔ Dual Extraction Process – Enhances absorption of beneficial compounds.
✔ Manufactured in a GMP-certified facility – High-quality control and testing standards.
Potential Drawbacks
⚠ Requires 3 capsules per serving – Some users may find this inconvenient.
⚠ Higher potency may cause mild stomach discomfort in sensitive individuals.
Customer Feedback
Value for Money:
✔ Many users find it affordable and effective, with high potency per serving.
✔ Some mention it’s worth the price, especially for an organic and third-party-tested supplement.
Health Benefits:
✔ Customers report improved immune function, reduced inflammation, and better liver health.
✔ Users feel a boost in energy and overall well-being.
Ease of Use:
✔ Easy to swallow, no strong taste or aftertaste.
✔ Some users note that taking 3 capsules daily can be slightly inconvenient.
Effectiveness:
✔ Many report better sleep, stress relief, and enhanced immunity.
✔ Some users feel a positive impact on brain fog and cognitive function.
Potential Side Effects:
⚠ A few users report mild stomach discomfort, though most find it tolerable.
Highlighted Ingredients
- Organic Red Reishi Mushroom Extract (Ganoderma lucidum & Ganoderma applanatum) – 1500mg per serving
- Vegetarian capsule shell (no artificial additives, preservatives, or fillers)
Best Suited For
This supplement is ideal for individuals who:
- Want to boost their immune system naturally.
- Need stress relief and better sleep.
- Are looking for anti-inflammatory and antioxidant support.
- Seek liver and kidney function support.
- Prefer a pure, organic, and high-potency reishi supplement.
Usage Recommendations
- Recommended Dosage: Take 3 capsules daily with water before a meal.
- For best results: Use consistently for at least 2-4 weeks to experience noticeable benefits.
- Stacking: Can be combined with other adaptogens like lion’s mane or ashwagandha for enhanced cognitive and stress-relief benefits.
Summary: Fresh Nutrition Organic Reishi Mushroom Capsules offer a high-potency, organic, and third-party-tested supplement with 40%+ alpha-glucan content. It’s ideal for those seeking immune support, stress relief, and improved energy levels, though the 3-capsule serving size may be inconvenient for some.
2. Best High-Potency Formula: Double Wood Reishi Mushroom Capsules
4.5 out of 5(15k+) from Amazon

Price: $19.95
Double Wood Supplements offers a highly potent 4:1 Reishi extract, providing 1,000mg per serving (equivalent to 4,000mg of reishi mushroom powder). This supplement includes both the fruiting body and mycelium, ensuring a full-spectrum mushroom extract for maximum benefits. With 300 capsules per bottle, it delivers an impressive 150-day supply, making it an excellent long-term investment for immune support and overall well-being.
Key Benefits
- High-Potency 4:1 Extract – 1,000mg per serving (equivalent to 4,000mg of reishi powder).
- Comprehensive Formula – Includes both the fruiting body and mycelium for full-spectrum benefits.
- Long-Lasting Supply – 300 capsules provide a 5-month supply.
- Supports Immune System – Influences white blood cell activity to enhance immunity.
- Third-Party Tested – Ensures purity, potency, and safety.
Main Ingredients
Each serving (2 capsules) contains:
- Reishi Mushroom Extract 4:1 – 1,000mg (Equivalent to 4,000mg of raw mushroom powder)
- Vegetarian Capsule Shell (Hypromellose, Vegetable Stearate, Silica)
Notable Advantages
✔ Full-Spectrum Mushroom Extract – Includes fruiting body & mycelium.
✔ Great Value – Large 300-capsule bottle for a 5-month supply.
✔ USA-Manufactured & GMP-Certified – High-quality production standards.
✔ Vegan, Non-GMO, and Free from Fillers – Clean and natural formulation.
Potential Drawbacks
⚠ Lower Reishi Dosage Per Serving Compared to Some Competitors – Some users prefer higher doses.
⚠ Not Dual-Extracted – Lacks alcohol extraction, which some believe enhances potency.
Customer Feedback
Value for Money:
✔ Users appreciate the affordable price and large bottle size.
✔ Considered a cost-effective option compared to similar products.
Health Benefits:
✔ Many customers report strong immune support, improved energy, and better mood.
✔ Some users mention enhanced cognitive function and memory recall.
Ease of Use:
✔ Capsules are easy to swallow and digest.
✔ No strong aftertaste or odor reported.
Effectiveness:
✔ Users notice mental clarity, reduced stress, and better sleep quality.
✔ Some customers report feeling more energized and refreshed.
Potential Side Effects:
⚠ A few users experience mild stomach discomfort, though it is uncommon.
Highlighted Ingredients
- Reishi Mushroom Extract 4:1 – 1,000mg per serving
- Vegetarian capsule shell (No artificial fillers or preservatives)
Best Suited For
This supplement is ideal for individuals who:
- Want long-term immune support with a cost-effective option.
- Need a gentler dosage of Reishi (compared to ultra-high-potency brands).
- Prefer a full-spectrum formula with both fruiting body & mycelium.
- Seek stress relief, better sleep, and cognitive enhancement.
Usage Recommendations
- Recommended Dosage: Take 2 capsules daily on an empty stomach for best absorption.
- For best results: Consistency is key—use for several weeks to notice full benefits.
- Stacking: Can be combined with Lion’s Mane or Cordyceps for added cognitive and energy-boosting benefits.
Summary: Double Wood Reishi Mushroom Capsules offer a high-quality, full-spectrum formula with a 5-month supply. It’s an ideal choice for those looking for long-term immune support, stress relief, and cognitive enhancement, though some may prefer a higher potency extract.
3. Best for Energy & Cognitive Function: Wellnest.Store Organic Reishi Mushroom Supplement
4.4 out of 5(85+) from Amazon

Price: $29.99
Wellnest.Store’s Organic Reishi Mushroom supplement is a USDA-certified organic product designed to enhance immune function, reduce stress, and improve sleep quality. With 800mg of pure organic Reishi mushroom per serving, this supplement is ideal for those looking for a clean and 100% natural option. The product is vegan, non-GMO, and gluten-free, ensuring high quality and safety standards.
Key Benefits
- Immune System Boost – Supports the body’s natural defense system and helps improve overall immunity.
- Adaptogenic Stress Relief – Assists in reducing stress and promoting a sense of calm.
- Better Sleep Quality – Helps regulate sleep cycles, leading to deeper and more restful sleep.
- USDA Organic Certified – Made with certified organic Reishi mushroom for purity and safety.
- Lab-Tested & Verified – Comes with third-party testing to ensure potency and cleanliness.
What It Contains
- Certified Organic Reishi Mushroom (Ganoderma lucidum) – 800mg per serving
- Capsule Type: Certified Organic Pullulan (Vegetable Capsule)
Pros
✔️ 100% Organic – USDA-certified and sourced naturally.
✔️ No Fillers or Additives – Contains pure Reishi mushroom extract.
✔️ Lab-Tested for Quality – Verified for potency and purity.
✔️ Vegan and Gluten-Free – Suitable for most dietary preferences.
✔️ Supports Relaxation and Sleep – Many users report improved mood and better sleep cycles.
Cons
❌ Lower Potency Compared to Extracts – 800mg per serving may be lower than concentrated Reishi extracts.
❌ Smaller Bottle Size – Only 60 capsules per bottle, requiring frequent repurchasing.
❌ Mild Earthy Taste – Some users may notice a slight mushroom aftertaste.
Customer Feedback
- Value for Money: Users find it slightly more expensive due to its organic certification but worth the cost for purity.
- Effectiveness: Many report enhanced immunity, reduced stress, and better sleep quality.
- Ease of Use: Capsules are easy to swallow, but some mention they need to take them consistently for best results.
- Side Effects: Very few side effects reported, though a small number of users experienced mild digestive discomfort.
Highlighted Ingredients
- Organic Reishi Mushroom (Ganoderma lucidum) – 800mg – Sourced naturally and certified organic for full-spectrum benefits.
Best Suited For
- Health-conscious individuals seeking a certified organic Reishi supplement
- People looking for natural stress relief and improved sleep quality
- Those who prefer a vegan, gluten-free, and additive-free supplement
Usage Recommendations
- Suggested Dose: Take 2 capsules daily, preferably in the morning on an empty stomach.
- Best Time to Take: Morning for energy and stress relief or evening for relaxation and sleep support.
Summary: Wellnest.Store’s Organic Reishi Mushroom supplement is a top-tier choice for those prioritizing purity, immune health, and stress relief. With USDA organic certification, lab testing, and a clean ingredient profile, it’s an excellent option for natural wellness seekers.
4. Best for Relaxation & Sleep: Troop Reishi Mushroom Gummies
4.4 out of 5(124+) from Amazon

Price: $44.99
Troop Reishi Mushroom Gummies offer a convenient and tasty way to incorporate the benefits of Reishi mushrooms into daily life. Each serving contains 4000mg of triple-extracted Reishi fruiting body, formulated to support stress relief, relaxation, sleep quality, and immune health. Unlike many mushroom supplements, these gummies are vegan, pectin-based, and flavored with real fruit extracts, making them an easy choice for those seeking a natural and effective wellness boost.
Key Benefits
- Supports Stress Management & Relaxation – Helps regulate cortisol levels and promotes calmness.
- Enhances Sleep Quality – Many users report better sleep and reduced anxiety.
- Immune System Support – Rich in antioxidants and adaptogens for better overall health.
- Triple-Extracted for Maximum Potency – Uses ultrasonic extraction to ensure optimal bioavailability.
- Made with Clean, Vegan Ingredients – Free from fillers, mycelium, and artificial additives.
Main Ingredients
- Reishi Mushroom Fruiting Body (Ganoderma lucidum) – 4000mg (Triple-extracted for higher potency)
- Pectin, Natural Fruit Flavoring, and Organic Cane Sugar
Notable Advantages
✔ 4000mg of Reishi Fruiting Body Extract – Higher potency compared to many mycelium-based products.
✔ Supports Sleep, Relaxation, and Emotional Balance – Helps lower cortisol and promote calmness.
✔ Third-Party Tested – Ensures purity and safety.
✔ Sustainably Sourced – Uses fully matured mushrooms with eco-friendly packaging.
✔ Delicious Mixed Berry Flavor – Makes daily supplementation enjoyable.
Potential Drawbacks
✖ Contains Sugar (3g per serving) – May not be ideal for those on a low-sugar diet.
✖ Not Suitable for Those Who Dislike Gummies – Some may prefer capsules or powders.
Customer Feedback
✅ Taste – Customers love the delicious mixed berry flavor, describing it as “not too sweet, just right.”
✅ Sleep Quality – Many users noticed improved REM sleep and better relaxation before bed.
✅ Calming Effects – Reports of reduced stress, anxiety, and improved mood after consistent use.
✅ Effectiveness – Some users say it works better than CBD oil for relaxation and sleep.
✅ Quality – Users praise the high-quality ingredients and clean formulation.
Highlighted Ingredients
- Reishi Mushroom Extract (4000mg) – Triple-extracted for enhanced bioavailability.
- Pectin (Plant-Based Gelling Agent) – Vegan-friendly alternative to gelatin.
- Organic Cane Sugar & Natural Flavors – Used for taste without artificial additives.
Best Suited For
✔ Those struggling with stress, anxiety, or trouble sleeping.
✔ People looking for a natural immune-boosting supplement.
✔ Anyone who prefers gummies over capsules or powders.
✔ Vegans and individuals avoiding artificial additives.
Usage Recommendations
- Suggested Use: Take 1–3 gummies per day, preferably in the evening for relaxation and sleep benefits.
- For Best Results: Consume consistently for at least 2–4 weeks.
- Storage: Keep in a cool, dry place, away from direct sunlight.
Summary: A great-tasting way to reduce stress, improve sleep, and boost overall well-being. These gummies are perfect for those who want a natural, vegan-friendly supplement without compromising on taste or effectiveness.
5. Best for Immune Support & Strength: Nutricost Reishi Mushroom Capsules
4.5 out of 5(203+) from Amazon

Price: $16.95
Nutricost Reishi Mushroom Capsules deliver 1,500mg of organic Reishi mushroom per serving in 120 vegetarian capsules. This supplement is CCOF Certified Organic, non-GMO, and free from gluten and soy. It is manufactured in a GMP-compliant, FDA-registered facility, ensuring quality and safety.
Key Benefits
- Immune System Support – Rich in bioactive compounds that help enhance immune function.
- Stress & Relaxation – Acts as an adaptogen to help the body manage stress and promote calmness.
- Cardiovascular Health – Supports circulatory health and blood pressure regulation.
- Antioxidant & Anti-Inflammatory – Helps fight oxidative stress and inflammation.
- Easy-to-Consume Capsules – Provides a high dose in just two capsules per day.
What It Contains
- Organic Reishi Mushroom (Ganoderma lucidum) (Fruiting Body) – 1,500mg per serving
- Other Ingredients: Pullulan capsule, magnesium stearate (vegetable source)
Pros
✔ High potency (1,500mg per serving)
✔ CCOF Certified Organic for purity and quality
✔ Vegetarian, non-GMO, gluten-free, and soy-free
✔ Manufactured in an FDA-registered and GMP-compliant facility
✔ Affordable pricing for a high-dosage supplement
Cons
✖ Larger capsule size may be difficult for some to swallow
✖ Lacks additional bioavailability enhancers (e.g., black pepper extract)
Customer Feedback
- Value for Money: Customers appreciate the affordable price for a high-potency organic supplement.
- Effectiveness: Many users report improved immune function, better stress management, and enhanced sleep quality.
- Ease of Use: Most find the capsules easy to take, though some mention their large size.
Who Should Use It?
- Individuals looking for a high-dose organic Reishi supplement
- Those seeking immune and stress support
- People who prefer vegetarian, gluten-free, and non-GMO supplements
Usage Recommendation
Take two capsules daily with water, preferably on an empty stomach for optimal absorption.
Summary: Nutricost Reishi Mushroom Capsules offer a powerful 1,500mg organic dose, ensuring immune and stress support at an affordable price. Its high quality and purity make it an excellent value for those seeking natural wellness.
6. Best Budget Option: Horbäach Reishi Mushroom Capsules
4.5 out of 5(117+) from Amazon

Price: $14.99
Horbäach Reishi Mushroom Capsules provide a highly concentrated 5:1 extract, delivering the equivalent of 5,000mg of raw Reishi mushroom per serving. Designed for immune support, stress management, and overall well-being, this supplement is non-GMO, gluten-free, and free from artificial additives.
Key Benefits
✔ Highly Potent Extract – 1,000mg of 5:1 extract per serving, equivalent to 5,000mg of raw Reishi mushroom.
✔ Supports Immune Health – Rich in polysaccharides and adaptogenic compounds.
✔ Promotes Relaxation & Stress Reduction – Helps regulate cortisol levels and enhances mood.
✔ Non-GMO & Allergen-Free – Free from gluten, wheat, yeast, lactose, artificial flavors, and preservatives.
What it Contains
- 1,000mg of Reishi Mushroom Extract (5:1 Concentration) – Equivalent to 5,000mg of raw mushroom.
- Other Ingredients: Gelatin capsule, vegetable magnesium stearate, silica, rice powder.
Pros
✔ High potency extract for maximum benefits
✔ Free from common allergens & artificial ingredients
✔ Large 200-capsule bottle for long-term use
Cons
✘ Not suitable for vegans (contains gelatin capsule)
✘ Some users may prefer whole mushroom powder over extract
Customer Feedback
- Value for Money: Users appreciate the strong potency and large bottle size at a reasonable price.
- Effectiveness: Many report improved immune health, stress reduction, and better sleep.
- Ease of Use: Capsules are easy to take, though some may find them slightly large.
- Overall Satisfaction: Highly rated for its purity, potency, and affordability.
Summary: Horbäach Reishi Mushroom Capsules deliver a highly concentrated 5:1 extract, providing strong immune and stress support. With 200 capsules per bottle, it’s a cost-effective and high-potency choice for those seeking maximum benefits.
What is Reishi Mushroom?
Reishi mushroom (Ganoderma lucidum) is a type of fungus that grows in hot and humid regions. It has been revered for its medicinal properties for thousands of years, particularly in Asian cultures. Unlike culinary mushrooms, reishi has a tough and woody texture, making it unsuitable for cooking but ideal for extraction into supplements.
Reishi mushrooms contain powerful bioactive compounds, including:
- Triterpenes – Known for their anti-inflammatory and liver-protective effects.
- Beta-glucans – Polysaccharides that help stimulate the immune system.
- Antioxidants – Support cellular health and combat oxidative stress.
Because of its unique composition, reishi is often taken in the form of capsules, powders, tinctures, or teas.
Health Benefits of Reishi Mushroom Supplements
Supports Immune Function
Reishi is best known for its ability to enhance immune system activity. Studies suggest that the beta-glucans in reishi mushrooms can stimulate white blood cells, helping the body fight infections and illnesses more effectively.
Reduces Stress and Promotes Relaxation
Reishi mushrooms act as adaptogens, helping the body adapt to stress. Research has shown that reishi can help reduce anxiety and promote better sleep by calming the nervous system.
Improves Sleep Quality
Unlike sedatives, reishi works naturally to balance the body’s stress response, making it easier to fall asleep and stay asleep. It is often used by those struggling with insomnia or poor sleep quality.
Supports Heart and Liver Health
Triterpenes found in reishi mushrooms have been linked to improved circulation and cholesterol balance, supporting cardiovascular health. Additionally, reishi may aid liver detoxification by promoting liver function.
Rich in Antioxidants
Reishi mushrooms contain potent antioxidants that help reduce oxidative stress, a key factor in aging and chronic diseases.
Summary: Reishi mushroom supplements support immune function, reduce stress, improve sleep, promote heart and liver health, and provide strong antioxidant benefits.
How to Choose the Best Reishi Mushroom Supplement
When selecting a reishi mushroom supplement, consider the following factors:
Source of the Mushroom
- Fruiting Body vs. Mycelium: The fruiting body contains higher levels of beneficial compounds, while mycelium (grown on grain) may have fewer active ingredients. Look for supplements derived from the fruiting body.
Extraction Method
- Dual Extraction (Water & Alcohol): Ensures maximum potency by extracting both water-soluble polysaccharides (immune-boosting) and alcohol-soluble triterpenes (anti-inflammatory).
Beta-Glucan and Triterpene Content
- High-quality supplements list beta-glucan and triterpene levels on the label. Aim for at least 20-30% beta-glucans for immune benefits.
Third-Party Testing and Certifications
- Choose brands that conduct third-party testing for purity and potency. Look for certifications like USDA Organic, Non-GMO, or NSF Certified for quality assurance.
Additives and Fillers
- Avoid supplements with unnecessary additives, artificial ingredients, or excessive binders. Pure reishi extract without fillers is the best option.
Summary: Look for fruiting body-based supplements with dual extraction, high beta-glucan content, third-party testing, and no artificial fillers for maximum effectiveness.
FAQs About Reishi Mushroom Supplements
When is the best time to take reishi mushroom supplements?
Reishi is best taken in the evening as it promotes relaxation and better sleep. However, it can also be taken in the morning for stress relief throughout the day.
Are there any side effects of taking reishi mushrooms?
Reishi is generally safe, but some people may experience mild digestive upset or dizziness when taken in high doses. Always start with a lower dose to assess tolerance.
How long does it take to see the benefits of reishi mushrooms?
It may take 2-4 weeks of consistent use to notice significant effects, such as improved sleep or reduced stress.
Can reishi mushrooms be taken with other supplements or medications?
Reishi may interact with blood thinners or immune-modulating drugs. If you are on medication, consult your healthcare provider before taking it.
Is reishi mushroom safe for long-term use?
Yes, reishi is considered safe for long-term use, but it is recommended to take occasional breaks to prevent tolerance buildup.
Conclusion
Reishi mushroom supplements offer a natural way to boost immunity, reduce stress, and enhance sleep quality. With their antioxidant-rich properties and potential cardiovascular benefits, they have become a staple for many seeking better overall wellness.